2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Cytochrome P450
  5. Cytochrome P450 Isoform
  6. Cytochrome P450 Agonist

Cytochrome P450 Agonist

Cytochrome P450 Agonists (4):

Cat. No. Product Name Effect Purity
  • HY-W587839
    4,8-Dioxa-3H-perfluorononanoic acid
    		Agonist
    4,8-Dioxa-3H-perfluorononanoic acid is a per- and polyfluoroalkyl substance, that exhibits affinity and potential agonistic activity to human pregnane X receptor (hPXR).
  • HY-W014701
    1,4-Dihydroxy-2-naphthoic acid
    		Agonist 99.60%
    1,4-Dihydroxy-2-naphthoic acid is an aryl hydrocarbon receptor (AhR) agonist. 1,4-Dihydroxy-2-naphthoic acid is also a bacterially derived metabolite and has anti-inflammatory activity.
  • HY-178053
    AHR agonist 10
    		Agonist
    AHR agonist 10 (B19) is a potent AHR agonist (EC50 = 2.01 nM). AHR agonist 10 can elevate the transcript levels of key AHR downstream pathway target genes, including CYP1A1 and CYP1B1. AHR agonist 10 can downregulate the expression levels of CD36, IL-18 and shows low cytotoxicity (>40 μM) to normal cells. AHR agonist 10 can suppress the expression of CCL5, CCL20, IL-6, IL-8, S100A9, TLR4, TNF-α, and TNFR1, demonstrating that AHR agonist 10 effectively modulate inflammatory responses through AHR dependent signaling pathways. AHR agonist 10 can be used for psoriasis research.
  • HY-169320
    SJPYT-328
    		Agonist
    SJPYT-328 is a PXR agonsit. PXR plays a major role in drug metabolism and drug-drug interactions.